Correlations of RAGE expression with patients’ survival rate
There was a total of 46 patients with MetPca. Of 46, 27 patients had
RAGE positive on specimens, and 19 had a negative expression on
specimens. When compared each other with respect to cancer recurrence,
cancer-specific mortality, and follow-up period (month); recurrence rate
(81,4% vs 78.9%, p=0.8), cancer-specific mortality (33.3% vs 26.3%,
p=0.58) were statistically found to be non -significant. (See table 2,
figure 2-3).
For the patients (total n=87) with localized prostate cancer, there were
47 patients with RAGE positive, 35 patients with RAGE negative. Five
patients in the LPCa group had a positive surgical margin, so these
patients were not included in the survival analysis. Comparison of these
two groups patients, we did not find a significant difference for the
cancer recurrence, duration of the follow-up, but we discovered that
biochemical recurrence rate was found significantly higher in RAGE
positive patients (p=0.00; table 2, figure 4).